Interactor 1: TRBP2 (Q15633)
RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein)
Gene: TARBP2

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 15973356, 24778252, 28174252, 19836333, 19820710, 19668211, 23622242, 16424907, 16142218, 25446899, 21858095, 19804757, 33328224
Identification Methods affinity chromatography technology, transmission electron microscopy, cosedimentation through density gradient, molecular sieving, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid, cosedimentation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~dsrm, Ribonuclease_3~dsrm
Common GO terms GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016442 - RISC complex
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 366
Hs

1 1922
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Ce
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ At
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024