HitPredict

Interactor 1: CIP4 (Q15642)
Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10)
Gene: TRIP10

Interactor 2: RHG44 (Q17R89)
Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)
Gene: ARHGAP44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.721

Property	Details
Experiments	25416956, 28514442, 32203420, 33961781, unassigned2213
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Hs			1 818
+	Hs
		1089301 FBP1L_HUMAN (1-601): 1.18e-109: 343: 51.40		RHG44_HUMAN (1-818): 1.01e-156: 479: 100.00
+	Hs
		1075791 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34
+	Hs
		1148383 FNBP1_HUMAN (1-601): 2.47e-103: 327: 49.35		RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34
+	Hs
		1075823 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		3BP1_HUMAN (1-589): 2.97e-86: 290: 39.22
+	Hs
		1075787 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		Q1RLN5_HUMAN (49-434): 8.75e-68: 242: 19.80
+	Hs
		1075798 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		RHG12_HUMAN (49-434): 1.45e-66: 239: 19.80
+	Dm
		112686 M9NE16_DROME (1-600): 2.71e-87: 285: 32.01		RG92B_DROME (1-735): 6.75e-82: 279: 22.91
+	Hs
		200194 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		SRGP3_HUMAN (12-710): 4.72e-73: 261: 14.75
+	Hs
		200200 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15
+	Hs
		253374 SRGP1_HUMAN (4-539): 1.06e-62: 225: 13.04		SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15
+	Hs
		200232 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		SH3G2_HUMAN (1-251): 1.54e-73: 245: 21.43
+	Hs
		200223 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		RHG24_HUMAN (150-610): 2.07e-67: 240: 17.95
+	Hs
		200231 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		SH3G1_HUMAN (1-251): 2.19e-70: 238: 21.43
+	Hs
		1148385 PACN1_HUMAN (155-597): 3.63e-17: 86.5: 9.91		RHG17_HUMAN (1-816): 1.66e-117: 378: 44.34
+	Hs
		561401 FER_HUMAN (1-489): 5.76e-58: 210: 15.52		RHG23_HUMAN (243-762): 1.53e-67: 246: 20.37
+	Hs
		561393 FER_HUMAN (1-489): 5.76e-58: 210: 15.52		RHG21_HUMAN (102-734): 7.8e-67: 244: 17.73
+	Hs
		1357492 PACN2_HUMAN (445-600): 4.72e-21: 98.8: 17.31		3BP1_HUMAN (1-589): 2.97e-86: 290: 39.22
+	Hs
		253304 SRG2C_HUMAN (6-285): 5.01e-20: 95.4: 15.84		SRGP2_HUMAN (12-782): 1.01e-71: 256: 15.15
+	Hs
		957808 RHG04_HUMAN (215-598): 4.49e-10: 64.9: 10.51		RHG04_HUMAN (108-683): 2.32e-71: 254: 17.63
+	Hs
		993032 SRGP1_HUMAN (4-539): 1.06e-62: 225: 13.04		RHG01_HUMAN (268-414): 6.18e-18: 89.4: 34.46