HitPredict

Interactor 1: CIP4 (Q15642)
Cdc42-interacting protein 4 (Protein Felic) (Salt tolerant protein) (hSTP) (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10)
Gene: TRIP10

Interactor 2: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	11431473, 25416956, 32296183, unassigned1304
Identification Methods	pull down, two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 601 Hs			1 881
+	Hs
		1148383 FNBP1_HUMAN (1-601): 2.47e-103: 327: 49.35		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		1075786 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		RHG44_HUMAN (1-754): 4.1e-106: 348: 46.20
+	Hs
		1089301 FBP1L_HUMAN (1-601): 1.18e-109: 343: 51.40		RHG44_HUMAN (1-754): 4.1e-106: 348: 46.20
+	Hs
		1075823 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		1075787 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		Q1RLN5_HUMAN (53-427): 1.31e-64: 234: 17.90
+	Hs
		1075798 CIP4_HUMAN (1-601): 2.77e-112: 349: 100.00		RHG12_HUMAN (53-427): 1.04e-63: 232: 17.90
+	Dm
		112686 M9NE16_DROME (1-600): 2.71e-87: 285: 32.01		RG92B_DROME (1-645): 9.92e-76: 264: 25.38
+	Hs
		1148385 PACN1_HUMAN (155-597): 3.63e-17: 86.5: 9.91		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		200200 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90
+	Hs
		253374 SRGP1_HUMAN (4-539): 1.06e-62: 225: 13.04		SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90
+	Hs
		200194 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		SRGP3_HUMAN (13-738): 1.18e-76: 272: 15.58
+	Hs
		200223 SRGP3_HUMAN (4-539): 1.39e-64: 231: 13.04		RHG24_HUMAN (181-607): 2.5e-68: 243: 19.82
+	Hs
		561393 FER_HUMAN (1-489): 5.76e-58: 210: 15.52		RHG21_HUMAN (10-685): 1.4e-69: 254: 16.46
+	Hs
		253304 SRG2C_HUMAN (6-285): 5.01e-20: 95.4: 15.84		SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90
+	Hs
		1357492 PACN2_HUMAN (445-600): 4.72e-21: 98.8: 17.31		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		993032 SRGP1_HUMAN (4-539): 1.06e-62: 225: 13.04		RHG01_HUMAN (250-412): 3.19e-19: 93.6: 32.73
+	Hs
		957808 RHG04_HUMAN (215-598): 4.49e-10: 64.9: 10.51		RHG04_HUMAN (30-677): 1.16e-66: 242: 18.12
+	Hs
		561401 FER_HUMAN (1-489): 5.76e-58: 210: 15.52		RHG23_HUMAN (241-445): 1.42e-16: 87: 28.23
+	Hs
		426941 FES_HUMAN (1-286): 2.72e-25: 113: 20.76		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54