HitPredict

Interactor 1: IKBB (Q15653)
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)
Gene: NFKBIB

Interactor 2: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_4
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 1134
+	Mm
		970499 ANK1_MOUSE (181-355): 1.47e-33: 133: 19.23		ANS1B_MOUSE (1-1133): 0: 621: 33.57
+	Hs
		121548 IKBE_HUMAN (25-333): 1.22e-60: 204: 31.72		ANR28_HUMAN (3-208): 2.79e-40: 164: 23.61
+	Mm
		1193396 DAPK1_MOUSE (1-260): 7.78e-50: 181: 22.22		MIB1_MOUSE (3-343): 1.71e-41: 168: 22.32
+	Hs
		167014 TNKS2_HUMAN (62-347): 1.71e-50: 183: 17.73		ANR28_HUMAN (3-208): 2.79e-40: 164: 23.61
+	Hs
		862070 DAPK1_HUMAN (1-260): 1.41e-48: 177: 22.22		MIB1_HUMAN (3-343): 1.07e-41: 168: 22.32
+	Hs
		862028 DAPK1_HUMAN (1-260): 1.41e-48: 177: 22.22		ANK2_HUMAN (180-837): 1.86e-34: 146: 13.55
+	Hs
		166919 ANK3_HUMAN (181-346): 6.08e-41: 155: 20.48		ANR28_HUMAN (3-208): 2.79e-40: 164: 23.61
+	Mm
		103608 ANK2_MOUSE (159-346): 4.02e-39: 150: 17.55		ANK3_MOUSE (180-812): 1.06e-40: 166: 12.56
+	Mm
		103591 ANK3_MOUSE (181-346): 1.12e-38: 148: 21.08		ANK3_MOUSE (180-812): 1.06e-40: 166: 12.56
+	Hs
		166913 ANK2_HUMAN (159-346): 4.02e-39: 150: 17.55		ANR28_HUMAN (3-208): 2.79e-40: 164: 23.61
+	Hs
		121553 IKBE_HUMAN (25-333): 1.22e-60: 204: 31.72		ANR17_HUMAN (2-102): 1.08e-14: 81.7: 23.76
+	Hs
		121592 IKBE_HUMAN (25-333): 1.22e-60: 204: 31.72		ANKH1_HUMAN (2-106): 1.43e-14: 81.3: 23.81
+	Hs
		1329533 TNKS2_HUMAN (62-347): 1.71e-50: 183: 17.73		TNKS2_HUMAN (289-680): 1.09e-12: 74.8: 9.90
+	Hs
		862012 DAPK1_HUMAN (1-260): 1.41e-48: 177: 22.22		DAPK1_HUMAN (70-268): 8.77e-14: 78.6: 32.66
+	Hs
		1021462 ANK3_HUMAN (181-346): 6.08e-41: 155: 20.48		Q9H4D1_HUMAN (60-245): 4.58e-19: 95.1: 38.17
+	Hs
		883496 ANK3_HUMAN (181-346): 6.08e-41: 155: 20.48		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63
+	Hs
		965154 ANK2_HUMAN (159-346): 4.02e-39: 150: 17.55		Q9H4D1_HUMAN (60-245): 4.58e-19: 95.1: 38.17
+	Hs
		883487 ANK2_HUMAN (159-346): 4.02e-39: 150: 17.55		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63