HitPredict

Interactor 1: IKBB (Q15653)
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)
Gene: NFKBIB

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11500849
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 530
+	Hs
		961412 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369415 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		587176 IKBB_HUMAN (1-356): 9.91e-80: 249: 100.00		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		257677 ANR17_HUMAN (2-172): 1.65e-30: 125: 18.71		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377350 IKBB_HUMAN (1-356): 9.91e-80: 249: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377254 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		257541 ANR17_HUMAN (2-172): 1.65e-30: 125: 18.71		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370687 KDIS_HUMAN (6-188): 2.58e-29: 121: 18.58		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269795 RAI14_HUMAN (94-266): 8.7e-11: 65.5: 27.17		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269396 ANR27_HUMAN (57-278): 9.75e-10: 62: 26.97		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377204 DAPK1_HUMAN (1-260): 1.41e-48: 177: 22.22		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		368977 BCL3_HUMAN (49-151): 2.25e-12: 69.8: 28.16		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370593 RAI14_HUMAN (94-266): 8.7e-11: 65.5: 27.17		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368970 NFKB1_HUMAN (28-140): 2.07e-10: 64.4: 29.57		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369957 ANKH1_HUMAN (6-91): 2.81e-10: 63.8: 16.28		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		257543 ANR17_HUMAN (2-172): 1.65e-30: 125: 18.71		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		587116 BCL3_HUMAN (49-151): 2.25e-12: 69.8: 28.16		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		587113 NFKB1_HUMAN (28-140): 2.07e-10: 64.4: 29.57		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		377081 NFKB1_HUMAN (28-140): 2.07e-10: 64.4: 29.57		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		587417 NFKB1_HUMAN (28-140): 2.07e-10: 64.4: 29.57		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30