HitPredict

Interactor 1: IKBB (Q15653)
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)
Gene: NFKBIB

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 14743216
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 356 Hs			1 1139
+	Mm
		100050 ANK2_MOUSE (159-346): 4.02e-39: 150: 17.55		SYGP1_MOUSE (2-1138): 0: 768: 43.44
+	Hs
		965139 ANK2_HUMAN (159-346): 4.02e-39: 150: 17.55		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		556720 ANK1_HUMAN (181-355): 2.01e-33: 133: 19.23		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		1299786 KDIS_HUMAN (6-188): 2.58e-29: 121: 18.58		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		1299772 RAI14_HUMAN (94-266): 8.7e-11: 65.5: 27.17		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		1040023 IKBB_HUMAN (1-356): 9.91e-80: 249: 100.00		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		809315 IKBB_HUMAN (1-356): 9.91e-80: 249: 100.00		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		809269 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		1021395 ANK3_HUMAN (181-346): 6.08e-41: 155: 20.48		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		587619 NFKB1_HUMAN (28-140): 2.07e-10: 64.4: 29.57		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Hs
		809460 RAI14_HUMAN (94-266): 8.7e-11: 65.5: 27.17		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10