HitPredict

Interactor 1: IKBB (Q15653)
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)
Gene: NFKBIB

Interactor 2: Q9UQC1 (Q9UQC1)
Heat shock protein 72
Gene: HSP70-1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 151
+	Hs
		713979 IKBB_HUMAN (1-356): 9.91e-80: 249: 100.00		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		504130 IKBB_HUMAN (1-356): 9.91e-80: 249: 100.00		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Hs
		564057 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		HSP76_HUMAN (1-150): 3.19e-78: 245: 85.33
+	Hs
		639827 IKBA_HUMAN (14-335): 5.39e-78: 243: 30.21		Q9UQC1_HUMAN (1-151): 8.55e-83: 241: 100.00
+	Hs
		639682 IKBA_HUMAN (14-335): 5.39e-78: 243: 30.21		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		503471 IKBA_HUMAN (14-335): 5.39e-78: 243: 30.21		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Hs
		961447 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		Q9UQC1_HUMAN (1-151): 8.55e-83: 241: 100.00
+	Hs
		713945 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		503906 NFKB2_HUMAN (35-347): 1.91e-71: 240: 31.15		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Mm
		926175 IKBA_MOUSE (7-335): 8.92e-77: 240: 31.07		HSP7C_MOUSE (1-150): 6.81e-76: 239: 87.33
+	Hs
		121603 IKBE_HUMAN (25-333): 1.22e-60: 204: 31.72		Q9UQC1_HUMAN (1-151): 8.55e-83: 241: 100.00
+	Hs
		121572 IKBE_HUMAN (25-333): 1.22e-60: 204: 31.72		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		121564 IKBE_HUMAN (25-333): 1.22e-60: 204: 31.72		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Hs
		483759 ANK2_HUMAN (159-346): 4.02e-39: 150: 17.55		HS71A_HUMAN (1-150): 1.18e-77: 243: 100.00
+	Hs
		503916 ANK2_HUMAN (159-346): 4.02e-39: 150: 17.55		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Hs
		714021 ANKK1_HUMAN (163-348): 2.22e-38: 147: 20.00		HS71L_HUMAN (1-150): 2.61e-76: 240: 91.33
+	Hs
		564002 BCL3_HUMAN (49-151): 2.25e-12: 69.8: 28.16		HSP76_HUMAN (1-150): 3.19e-78: 245: 85.33
+	Mm
		638457 NFKB1_MOUSE (14-140): 5.94e-11: 65.9: 29.46		HS71A_MOUSE (1-150): 9.78e-78: 243: 95.33
+	Hs
		504882 RAI14_HUMAN (94-266): 8.7e-11: 65.5: 27.17		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33
+	Hs
		503415 NFKB1_HUMAN (28-140): 2.07e-10: 64.4: 29.57		HSP7C_HUMAN (1-150): 6.81e-76: 239: 87.33