HitPredict

Interactor 1: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LIM~LRR_8
Common GO terms	GO:0005886 - plasma membrane GO:0030335 - positive regulation of cell migration
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 839
+	Hs
		1081638 LIMD1_HUMAN (1-475): 1.08e-69: 236: 25.36		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		609300 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		607981 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		508136 LPP_HUMAN (3-475): 1.2e-65: 224: 38.82		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		385342 PDLI5_HUMAN (249-334): 7.45e-09: 60: 20.93		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		609352 ABLM2_HUMAN (279-368): 1e-10: 65.9: 39.56		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		508024 ZYX_HUMAN (91-467): 2.51e-15: 80.4: 18.02		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		434304 TES_HUMAN (141-457): 1.24e-56: 195: 19.09		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		968385 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		434295 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		968450 LPP_HUMAN (3-475): 1.2e-65: 224: 38.82		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		968509 TES_HUMAN (141-457): 1.24e-56: 195: 19.09		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		435793 TES_HUMAN (141-457): 1.24e-56: 195: 19.09		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		435580 PAXI_HUMAN (258-395): 1.68e-28: 120: 25.90		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		411503 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		823515 PAXI_HUMAN (258-395): 1.68e-28: 120: 25.90		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03