HitPredict

Interactor 1: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Interactor 2: Q5VU62 (Q5VU62)
TPM3 protein (cDNA FLJ32435 fis, clone SKMUS2001287, highly similar to Tropomyosin alpha-3 chain)
Gene: TPM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 158
+	Hs
		418964 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		TPM3_HUMAN (1-158): 1.13e-44: 149: 100.00
+	Hs
		932007 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		TPM4_HUMAN (1-158): 5.95e-39: 134: 76.58
+	Hs
		451325 TES_HUMAN (141-457): 1.24e-56: 195: 19.09		TPM1_HUMAN (1-158): 2.83e-44: 148: 90.51
+	Hs
		419055 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		TPM3_HUMAN (1-158): 1.13e-44: 149: 100.00
+	Hs
		451318 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		TPM1_HUMAN (1-158): 2.83e-44: 148: 90.51
+	Hs
		110806 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		H7BYY1_HUMAN (1-158): 1e-42: 143: 67.09
+	Hs
		932058 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		TPM4_HUMAN (1-158): 5.95e-39: 134: 76.58
+	Hs
		434438 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		TPM2_HUMAN (1-158): 5.84e-37: 129: 86.71
+	Mm
		886037 PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03		TPM1_MOUSE (1-158): 2.33e-44: 149: 91.14
+	Mm
		886046 PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03		TPM2_MOUSE (1-158): 5.84e-37: 129: 86.71
+	Hs
		434422 PDLI5_HUMAN (249-334): 7.45e-09: 60: 20.93		TPM2_HUMAN (1-158): 5.84e-37: 129: 86.71