HitPredict

Interactor 1: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Interactor 2: DEFI8 (Q6ZN54)
Differentially expressed in FDCP 8 homolog (DEF-8)
Gene: DEF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 512
+	Mm
		661014 LDB3_MOUSE (122-459): 9.24e-94: 300: 23.78		KPCD_MOUSE (156-340): 4.03e-39: 152: 14.49
+	Mm
		554947 LDB3_MOUSE (122-459): 9.24e-94: 300: 23.78		KPCE_MOUSE (151-250): 4.12e-23: 105: 18.35
+	Mm
		934638 LDB3_MOUSE (122-459): 9.24e-94: 300: 23.78		KPCB_MOUSE (151-269): 5.86e-21: 98.3: 15.00
+	Mm
		593492 LDB3_MOUSE (122-459): 9.24e-94: 300: 23.78		KPCA_MOUSE (151-250): 4.41e-19: 92.5: 16.83
+	Mm
		930579 LDB3_MOUSE (122-459): 9.24e-94: 300: 23.78		KPCG_MOUSE (151-270): 1.49e-18: 90.9: 15.70
+	Hs
		566498 TES_HUMAN (141-457): 1.24e-56: 195: 19.09		KPCA_HUMAN (151-250): 2.8e-20: 96.3: 16.83
+	Hs
		408685 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		KPCB_HUMAN (151-269): 6.29e-21: 98.3: 15.00
+	Rn
		448415 PDLI5_RAT (70-334): 2.8e-10: 64.6: 14.59		KPCE_RAT (151-250): 3.14e-23: 105: 18.35
+	Mm
		554924 PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03		KPCE_MOUSE (151-250): 4.12e-23: 105: 18.35
+	Hs
		969104 PDLI5_HUMAN (249-334): 7.45e-09: 60: 20.93		KPCE_HUMAN (151-250): 8.06e-23: 104: 17.43
+	Rn
		934617 PDLI5_RAT (70-334): 2.8e-10: 64.6: 14.59		KPCB_RAT (151-269): 5.86e-21: 98.3: 15.00
+	Hs
		408660 PDLI5_HUMAN (249-334): 7.45e-09: 60: 20.93		KPCB_HUMAN (151-269): 6.29e-21: 98.3: 15.00