HitPredict

Interactor 1: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 476 Hs			1 400
+	Hs
		1326768 LIMD1_HUMAN (1-475): 1.08e-69: 236: 25.36		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		808640 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1274169 LPP_HUMAN (3-475): 1.2e-65: 224: 38.82		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		808849 AJUBA_HUMAN (2-473): 1.32e-59: 206: 25.70		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808988 TES_HUMAN (141-457): 1.24e-56: 195: 19.09		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1326752 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		1080775 ZYX_HUMAN (91-467): 2.51e-15: 80.4: 18.02		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		808955 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1076559 TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Dm
		1115157 AJUBA_DROME (7-475): 9.64e-63: 218: 26.64		YAP1_DROME (17-223): 5.05e-46: 164: 22.80
+	Hs
		808647 ZYX_HUMAN (91-467): 2.51e-15: 80.4: 18.02		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1294450 AJUBA_HUMAN (2-473): 1.32e-59: 206: 25.70		SAV1_HUMAN (2-252): 3.57e-48: 169: 15.89
+	Hs
		63209 WTIP_HUMAN (167-474): 5.41e-58: 199: 34.19		SAV1_HUMAN (2-252): 3.57e-48: 169: 15.89
+	Hs
		1327916 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		125735 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1336088 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		SMUF1_HUMAN (55-362): 3.85e-51: 184: 16.62
+	Mm
		1143674 TGFI1_MOUSE (11-337): 5.73e-13: 72.5: 20.17		ITCH_MOUSE (119-356): 8.31e-59: 207: 15.66
+	Hs
		1344053 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		WWC3_HUMAN (119-258): 4.68e-41: 156: 18.57
+	Hs
		808283 PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		200165 TGFI1_HUMAN (268-337): 1.32e-11: 68.3: 27.14		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00