HitPredict

Interactor 1: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Interactor 2: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 2036
+	Hs
		915756 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		925359 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		564573 RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		894131 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		892432 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		RGPA1_HUMAN (1-2036): 0: 2954: 100.00
+	Hs
		915714 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		564550 RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49		RGPA2_HUMAN (1-2030): 0: 2671: 49.46
+	Hs
		1076642 RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		196428 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22
+	Hs
		916041 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88
+	Hs
		925514 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91
+	Hs
		915799 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		230232 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Hs
		925407 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		835036 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		TSC2_HUMAN (1727-2033): 1.18e-96: 349: 23.90
+	Hs
		564595 RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		894180 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67
+	Hs
		230233 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		SI1L3_HUMAN (1691-2016): 1.32e-100: 362: 18.83
+	Dm
		776929 RAC1_DROME (2-191): 5.11e-73: 220: 38.58		X2JDH0_DROME (1637-2013): 4.12e-102: 367: 21.16
+	Dm
		776932 RAC1_DROME (2-191): 5.11e-73: 220: 38.58		X2JJU0_DROME (1637-2013): 3.69e-102: 367: 21.16