HitPredict

Interactor 1: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Interactor 2: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008360 - regulation of cell shape GO:0031267 - small GTPase binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 1253
+	Hs
		915782 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Mm
		1143609 RHOC_MOUSE (6-185): 6.48e-85: 250: 42.25		CYFP1_MOUSE (1-1253): 0: 2079: 99.04
+	Hs
		925386 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		894162 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Mm
		925800 RAC1_MOUSE (2-191): 2.63e-75: 226: 39.09		CYFP1_MOUSE (1-1253): 0: 2079: 99.04
+	Hs
		545463 RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		892449 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		951104 RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		900624 RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		925513 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		545555 RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		892535 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		951231 RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		900789 RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Dm
		776913 RAC1_DROME (2-191): 5.11e-73: 220: 38.58		CYFIP_DROME (1-1253): 0: 1903: 65.73
+	At
		1105123 RAC3_ARATH (5-191): 1.18e-71: 216: 38.54		PIR_ARATH (5-1240): 0: 1535: 28.88