Interactor 1: G5EFG5 (G5EFG5)
Mismatch repair endonuclease PMS2
Gene: pms-2

Interactor 2: Q9XU10 (Q9XU10)
DNA mismatch repair protein S5 domain-containing protein
Gene: mlh-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 12679813, 14704431, 11778048
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3, Mlh1_C~MutL_C
Common GO terms GO:0005524 - ATP binding
GO:0006298 - mismatch repair
GO:0016446 - somatic hypermutation of immunoglobulin genes
GO:0016887 - ATP hydrolysis activity
GO:0030983 - mismatched DNA binding
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 805
Ce

1 758
+ Hs
+ Dm
+ Sc
+ Dm
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Ec
+ Sc

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Last updated: 15 Jul 2024