HitPredict

Interactor 1: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Interactor 2: GDIR3 (Q99819)
Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma)
Gene: ARHGDIG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11809807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Rho_GDI
Common GO terms	GO:0005886 - plasma membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 225
+	Hs
		915920 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		GDIR3_HUMAN (1-225): 1.49e-115: 330: 100.00
+	Hs
		854792 RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Hs
		854855 RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00		GDIR2_HUMAN (47-225): 5.49e-96: 280: 60.89
+	Hs
		925561 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		GDIR3_HUMAN (1-225): 1.49e-115: 330: 100.00
+	Hs
		436218 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Hs
		854767 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Hs
		894357 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		GDIR3_HUMAN (1-225): 1.49e-115: 330: 100.00
+	Mm
		925816 RAC1_MOUSE (2-191): 2.63e-75: 226: 39.09		GDIR1_MOUSE (36-225): 6.84e-105: 302: 60.53
+	Hs
		854769 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Hs
		854760 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Mm
		892716 RAC3_MOUSE (2-171): 3.86e-72: 218: 41.81		GDIR1_MOUSE (36-225): 6.84e-105: 302: 60.53
+	Hs
		545278 RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Hs
		854759 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		GDIR1_HUMAN (36-225): 1.46e-104: 301: 61.05
+	Mm
		892713 RAC3_MOUSE (2-171): 3.86e-72: 218: 41.81		GDIR2_MOUSE (27-225): 2.17e-101: 293: 56.22
+	Hs
		854851 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		GDIR2_HUMAN (47-225): 5.49e-96: 280: 60.89
+	Hs
		545279 RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07		GDIR2_HUMAN (47-225): 5.49e-96: 280: 60.89
+	Hs
		854847 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		GDIR2_HUMAN (47-225): 5.49e-96: 280: 60.89
+	Dm
		816393 RHO1_DROME (6-180): 2.06e-79: 236: 41.76		Q9VW59_DROME (28-223): 7.56e-84: 249: 42.21
+	Ce
		975573 RAC1_CAEEL (2-191): 1.19e-74: 224: 40.10		GDIR_CAEEL (47-222): 9.12e-76: 228: 37.29
+	Cl
		47354 RAC1_CANLF (2-191): 2.63e-75: 226: 39.09		A0A8I3N6C6_CANLF (36-225): 9.11e-70: 212: 44.21