HitPredict

Interactor 1: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 2365
+	Hs
		915963 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		925603 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		564677 RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		915771 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		254483 RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		894572 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		MUC12_HUMAN (3-1364): 6.12e-46: 186: 11.77
+	Hs
		254433 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		254467 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		254468 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		254445 RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		254462 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		724757 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		725125 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Ce
		136793 RAC1_CAEEL (2-191): 1.19e-74: 224: 40.10		UNC89_CAEEL (392-957): 7.22e-20: 100: 14.04
+	Hs
		297809 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18
+	Hs
		297822 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18
+	Hs
		551652 CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		297823 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18
+	Hs
		925204 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82
+	Hs
		297819 RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81		K0754_HUMAN (38-333): 3.28e-10: 68.4: 18.18