HitPredict

Interactor 1: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1139
+	Hs
		436564 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		916057 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		1076617 RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Hs
		915746 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Hs
		925347 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Hs
		436465 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		915658 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		925259 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		436384 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Hs
		915797 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Hs
		436197 RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		809251 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		925404 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Mm
		925821 RAC1_MOUSE (2-191): 2.63e-75: 226: 39.09		IQGA1_MOUSE (126-751): 1.8e-133: 446: 12.33
+	Hs
		809255 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		925282 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		RASA3_HUMAN (169-570): 2.21e-123: 401: 25.97
+	Dd
		710113 RAC1A_DICDI (2-191): 5.87e-76: 227: 39.09		RGAA_DICDI (183-692): 1.51e-109: 363: 13.26
+	Hs
		598456 RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Dd
		136239 RAC1A_DICDI (2-191): 5.87e-76: 227: 39.09		GAPA_DICDI (214-671): 2.19e-96: 328: 13.42
+	Hs
		598457 RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17