HitPredict

Interactor 1: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Interactor 2: STXB4 (Q6ZWJ1)
Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (STX4-interacting protein) (Synip)
Gene: STXBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	28514442, 27432908, 28675297, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1187 Hs			1 553
+	Hs
		1087905 PTN21_HUMAN (1-1187): 0: 817: 52.29		STXB4_HUMAN (1-553): 0: 815: 100.00
+	Hs
		876394 PTN14_HUMAN (1-1187): 0: 985: 100.00		AFAD_HUMAN (1-218): 2.12e-34: 141: 19.38
+	Hs
		1020184 PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36		STXB4_HUMAN (1-553): 0: 815: 100.00
+	Hs
		1076899 PTN14_HUMAN (1-1187): 0: 985: 100.00		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Hs
		876508 E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33		AFAD_HUMAN (1-218): 2.12e-34: 141: 19.38
+	Hs
		577018 PTPRA_HUMAN (428-1181): 5.96e-139: 442: 18.42		PTN13_HUMAN (3-185): 4.49e-13: 74.5: 18.75
+	Hs
		150882 RADI_HUMAN (18-364): 3.83e-121: 388: 20.68		DVL2_HUMAN (2-192): 2.86e-30: 127: 16.90
+	Hs
		719764 RADI_HUMAN (18-364): 3.83e-121: 388: 20.68		NEB2_HUMAN (7-242): 4.94e-30: 127: 18.03
+	Hs
		547188 EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96		NEB2_HUMAN (7-242): 4.94e-30: 127: 18.03
+	Hs
		1256898 E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Hs
		547242 EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96		LIN7C_HUMAN (12-101): 3.91e-23: 99: 34.44
+	Hs
		158302 E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33		LIN7A_HUMAN (12-101): 4.07e-22: 97.1: 35.56
+	Hs
		876371 PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36		AFAD_HUMAN (1-218): 2.12e-34: 141: 19.38
+	Hs
		1020198 PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Hs
		617129 PTPRG_HUMAN (289-1185): 4.53e-60: 228: 12.65		PARD3_HUMAN (5-241): 1.88e-24: 110: 18.60
+	Rn
		94280 F1LXJ9_RAT (268-1183): 1.59e-68: 255: 12.60		MAGI2_RAT (21-157): 4.55e-15: 80.6: 21.83
+	Mm
		1145445 PTN13_MOUSE (1-877): 1.89e-69: 258: 13.38		PTN13_MOUSE (13-234): 1.33e-12: 72.9: 15.79
+	Rn
		1143999 PTPRZ_RAT (271-1185): 5.45e-58: 222: 12.18		DLG2_RAT (17-104): 1.77e-23: 107: 28.26