HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26638075, 26496610, 34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 1584
+	Hs
		1131889 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		1077185 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		1357803 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		807736 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		1077080 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Hs
		944717 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27
+	Hs
		1077175 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		297830 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		K0754_HUMAN (564-1101): 7.33e-14: 79.4: 11.88