HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: CE350 (Q5VT06)
Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)
Gene: CEP350

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26496610, 34079125, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CAP_GLY~EB1
Common GO terms	GO:0005813 - centrosome GO:0071539 - protein localization to centrosome GO:1905515 - non-motile cilium assembly
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 3117
+	Hs
		1137867 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		CE350_HUMAN (1-3117): 0: 2565: 100.00
+	Hs
		317258 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		PCNT_HUMAN (1316-2932): 1.6e-35: 152: 12.02
+	Hs
		969589 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		CENPE_HUMAN (1304-2951): 1.81e-32: 142: 10.39
+	Hs
		1068538 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		PLEC_HUMAN (1444-2943): 4.71e-31: 137: 11.26
+	Hs
		317379 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		PCNT_HUMAN (1316-2932): 1.6e-35: 152: 12.02
+	Hs
		1077108 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		CP250_HUMAN (1259-2387): 1.42e-23: 112: 10.97
+	Hs
		675173 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		CLIP1_HUMAN (2438-2907): 5.59e-21: 103: 16.77
+	Mm
		1142239 MARE1_MOUSE (1-257): 1.2e-149: 420: 96.89		CLIP2_MOUSE (2460-2629): 5.65e-20: 100: 28.90
+	Hs
		1077154 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		CLIP2_HUMAN (2460-2631): 2.61e-19: 98: 28.57
+	Hs
		1051289 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49
+	Hs
		675249 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		CLIP1_HUMAN (2438-2907): 5.59e-21: 103: 16.77
+	Mm
		1161106 MARE3_MOUSE (1-268): 9.7e-135: 383: 63.70		CLIP2_MOUSE (2460-2629): 5.65e-20: 100: 28.90
+	Sp
		945169 MAL3_SCHPO (16-260): 3.99e-89: 268: 34.13		TIP1_SCHPO (2497-2892): 2.55e-53: 197: 18.95
+	Hs
		1051521 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49
+	Sc
		514563 BIM1_YEAST (16-257): 3.5e-85: 259: 32.63		BIK1_YEAST (2496-2932): 1.53e-50: 188: 15.77
+	Dm
		1368643 Q9XZ57_DROME (1-265): 4e-126: 361: 52.60		CL190_DROME (1332-2269): 5.94e-09: 64.5: 15.64
+	Hs
		1051288 MARE2_HUMAN (1-267): 3.67e-121: 350: 55.16		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49