HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: NAV1 (Q8NEY1)
Neuron navigator 1 (Pore membrane and/or filament-interacting-like protein 3) (Steerin-1) (Unc-53 homolog 1) (unc53H1)
Gene: NAV1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	25065758, 29162697, 34079125, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001578 - microtubule bundle formation GO:0005874 - microtubule
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 1877
+	Hs
		1243703 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		NAV1_HUMAN (1-1877): 0: 748: 100.00
+	Hs
		1077016 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		NAV3_HUMAN (57-1877): 3.46e-164: 558: 37.13
+	Hs
		1077017 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		NAV2_HUMAN (57-1877): 2.29e-150: 518: 33.13
+	Hs
		1217645 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		NAV2_HUMAN (57-1877): 2.29e-150: 518: 33.13
+	Hs
		1264917 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		CTTB2_HUMAN (781-1828): 1.32e-124: 434: 14.78
+	Hs
		297830 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		K0754_HUMAN (26-425): 9.52e-18: 92.7: 12.29
+	Hs
		1077175 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		SRRM2_HUMAN (486-1510): 5.71e-15: 83.5: 9.90