HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: HOOK2 (Q96ED9)
Protein Hook homolog 2 (h-hook2) (hHK2)
Gene: HOOK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 719
+	Hs
		1077041 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		DLG5_HUMAN (187-645): 1.59e-15: 83: 16.84
+	Hs
		1076956 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		GRDN_HUMAN (37-565): 6.81e-15: 81.3: 14.55
+	Hs
		1077011 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		HOOK3_HUMAN (240-711): 2.67e-12: 72.4: 15.04
+	Hs
		1077162 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		HOOK1_HUMAN (328-719): 5.67e-10: 64.7: 11.88
+	Hs
		551719 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		DESP_HUMAN (181-664): 2.01e-09: 63.4: 13.06
+	Hs
		1255145 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		DLG5_HUMAN (187-645): 1.59e-15: 83: 16.84
+	Hs
		1113865 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		GRDN_HUMAN (37-565): 6.81e-15: 81.3: 14.55
+	Hs
		254524 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		ROCK2_HUMAN (179-532): 3.76e-09: 62.2: 14.32