HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26496610, 29162697, 34079125, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0035371 - microtubule plus-end GO:0036064 - ciliary basal body GO:0051301 - cell division GO:0071539 - protein localization to centrosome and 1 others more... GO:0097431 - mitotic spindle pole
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 1193
+	Hs
		1300744 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		297830 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		K0754_HUMAN (4-1190): 2.58e-24: 113: 8.66
+	Hs
		551719 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		1068538 MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		254524 MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70		ROCK2_HUMAN (526-1193): 1.76e-21: 103: 11.92