HitPredict

Interactor 1: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Interactor 2: MARE3 (Q9UPY8)
Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3)
Gene: MAPRE3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 30217970, 27107012, 29997244, 32296183, 34079125, 25416956, 23001180, 26186194, 28514442, 27173435, 29162697, 26264872, 33961781, 35271311, 34349018, 31515488, unassigned1304, 32814053
Identification Methods two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, proximity labelling technology, pull down, cross-linking study, validated two hybrid, barcode fusion genetics two hybrid, split luciferase complementation, luminescence based mammalian interactome mapping and 4 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, EB1~EB1
Common GO terms GO:0005815 - microtubule organizing center
GO:0008104 - protein localization
GO:0019901 - protein kinase binding
GO:0031110 - regulation of microtubule polymerization or depolymerization
GO:0035371 - microtubule plus-end
and 6 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 268
Hs

1 281
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Last updated: 15 Jul 2024