HitPredict

Interactor 1: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Interactor 2: NLGN2 (Q8NFZ4)
Neuroligin-2
Gene: NLGN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	9278515
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0016020 - membrane GO:0098609 - cell-cell adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 835
+	Hs
		1077290 DLG2_HUMAN (1-870): 0: 755: 100.00		NLGN3_HUMAN (1-835): 0: 813: 60.05
+	Hs
		1077282 DLG2_HUMAN (1-870): 0: 755: 100.00		NLGN1_HUMAN (6-835): 0: 808: 59.64
+	Rn
		1144055 DLG2_RAT (1-870): 0: 740: 94.94		NLGN2_RAT (1-835): 0: 799: 98.21
+	Rn
		1144025 DLG2_RAT (1-870): 0: 740: 94.94		NLGN1_RAT (1-835): 0: 795: 61.14
+	Hs
		942360 DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93		NLGNX_HUMAN (1-835): 0: 823: 60.47
+	Mm
		1143408 DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93		NLGN3_MOUSE (1-835): 0: 819: 62.38
+	Mm
		57108 DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93		A2AGI2_MOUSE (1-835): 0: 816: 60.60
+	Hs
		942388 DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93		NLGN3_HUMAN (1-835): 0: 813: 60.05
+	Hs
		942361 DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93		NLGN1_HUMAN (6-835): 0: 808: 59.64
+	Mm
		1143338 DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93		NLGN2_MOUSE (1-835): 0: 802: 98.09
+	Hs
		1271033 DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40		NLGN3_HUMAN (1-835): 0: 813: 60.05
+	Rn
		677789 DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93		NLGN2_RAT (1-835): 0: 799: 98.21
+	Rn
		1144051 DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23		NLGN2_RAT (1-835): 0: 799: 98.21
+	Hs
		1231765 DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40		NLGN1_HUMAN (6-835): 0: 808: 59.64
+	Rn
		677788 DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93		NLGN1_RAT (1-835): 0: 795: 61.14
+	Hs
		942363 DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93		NLGN2_HUMAN (1-835): 0: 795: 100.00
+	Rn
		1144023 DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23		NLGN1_RAT (1-835): 0: 795: 61.14
+	Hs
		1245078 DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40		NLGN2_HUMAN (1-835): 0: 795: 100.00
+	Dm
		677696 DLG1_DROME (321-774): 3.5e-09: 62.9: 12.92		Q7KT70_DROME (12-634): 3.06e-154: 477: 28.66