HitPredict

Interactor 1: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1073 Hs			1 4911
+	Hs
		554310 MUC1_HUMAN (241-1069): 1.4e-45: 181: 9.20		EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99
+	Hs
		1018501 T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00		CHD3_HUMAN (390-526): 1.86e-31: 139: 21.38
+	Hs
		1080263 MUC4_HUMAN (144-1073): 6.86e-18: 92: 9.95		EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99
+	Hs
		1080420 CHD7_HUMAN (558-1071): 5.93e-13: 75.8: 9.26		EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99
+	Hs
		577647 SON_HUMAN (486-849): 3.79e-10: 66.5: 16.71		EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99
+	Hs
		1080127 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		EZH2_HUMAN (4563-4893): 4.31e-83: 294: 20.99
+	Hs
		1077360 T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00		KMT2B_HUMAN (1985-2617): 4.3e-09: 65.8: 12.11
+	Dm
		1129083 Q9VLS7_DROME (1-689): 2.91e-10: 67: 9.43		SET1_DROME (4698-4911): 6.13e-60: 232: 34.57
+	Hs
		1303336 MUC4_HUMAN (144-1073): 6.86e-18: 92: 9.95		MUC4_HUMAN (1303-3039): 1.48e-46: 189: 11.46
+	Hs
		165699 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		SET1A_HUMAN (4638-4911): 3.38e-54: 214: 29.73
+	Hs
		152553 KMT2D_HUMAN (25-798): 6.74e-09: 62.7: 13.60		SET1A_HUMAN (4638-4911): 3.38e-54: 214: 29.73
+	Hs
		1059674 ADNP2_HUMAN (653-1067): 2.23e-09: 63.7: 13.00		CHD4_HUMAN (83-436): 3.08e-38: 161: 13.56
+	Hs
		975285 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		KMT2A_HUMAN (159-332): 7.57e-32: 140: 22.16
+	Dm
		51534 A1Z6M0_DROME (192-991): 3.85e-21: 102: 14.55		Q7K3G5_DROME (359-435): 1.38e-13: 79: 42.50
+	Hs
		1243853 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		SET1B_HUMAN (4778-4911): 3.56e-24: 115: 51.11
+	Hs
		1153496 ADNP2_HUMAN (653-1067): 2.23e-09: 63.7: 13.00		CHD5_HUMAN (285-390): 1.98e-22: 109: 20.16
+	Dm
		113976 M9PB30_DROME (2-390): 5.96e-11: 69.3: 8.42		M9PB30_DROME (3022-3853): 1.79e-13: 80.4: 10.32
+	Hs
		1262689 ATX2L_HUMAN (407-1071): 1.61e-12: 73.9: 9.50		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		1243852 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		KMT2B_HUMAN (1985-2617): 4.3e-09: 65.8: 12.11
+	Hs
		152667 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82