HitPredict

Interactor 1: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Interactor 2: NRBP (Q9UHY1)
Nuclear receptor-binding protein
Gene: NRBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	17353931, 32160551, 33961781, 35271311, 32707033
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1073 Hs			1 535
+	Hs
		1077348 T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00		NRBP2_HUMAN (55-519): 7.34e-122: 368: 60.84
+	Hs
		1077338 T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00		WNK1_HUMAN (5-338): 4.13e-107: 353: 30.57
+	Hs
		1355633 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		NRBP_HUMAN (1-535): 1.47e-146: 433: 100.00
+	Hs
		1304682 T22D3_HUMAN (959-1060): 8.88e-24: 99.9: 67.96		NRBP_HUMAN (1-535): 1.47e-146: 433: 100.00
+	Hs
		256836 T22D2_HUMAN (230-642): 1.86e-10: 67.3: 10.41		NRBP_HUMAN (1-535): 1.47e-146: 433: 100.00
+	Hs
		1345645 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		NRBP2_HUMAN (55-519): 7.34e-122: 368: 60.84
+	Hs
		1304681 T22D3_HUMAN (959-1060): 8.88e-24: 99.9: 67.96		NRBP2_HUMAN (55-519): 7.34e-122: 368: 60.84
+	Dm
		1098027 BUN2_DROME (970-1059): 3.36e-19: 96.2: 62.22		NRBP_DROME (3-516): 1.35e-119: 367: 48.39
+	Hs
		1330751 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		WNK1_HUMAN (5-338): 4.13e-107: 353: 30.57
+	Hs
		1317207 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		WNK3_HUMAN (6-532): 2.39e-104: 345: 25.73
+	Hs
		256831 T22D2_HUMAN (230-642): 1.86e-10: 67.3: 10.41		NRBP2_HUMAN (55-519): 7.34e-122: 368: 60.84
+	Hs
		1377724 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		WNK2_HUMAN (3-348): 1.01e-98: 329: 30.03
+	Hs
		1354609 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		STK39_HUMAN (68-530): 2.53e-105: 328: 14.96
+	Hs
		161716 GAK_HUMAN (455-793): 2.95e-10: 66.9: 18.82		WNK1_HUMAN (5-338): 4.13e-107: 353: 30.57
+	Hs
		99455 GAK_HUMAN (455-793): 2.95e-10: 66.9: 18.82		F5GWT4_HUMAN (5-338): 3.98e-107: 353: 30.57
+	Hs
		256827 T22D2_HUMAN (230-642): 1.86e-10: 67.3: 10.41		WNK3_HUMAN (6-532): 2.39e-104: 345: 25.73
+	Hs
		161708 GAK_HUMAN (455-793): 2.95e-10: 66.9: 18.82		WNK3_HUMAN (6-532): 2.39e-104: 345: 25.73
+	Hs
		256834 T22D2_HUMAN (230-642): 1.86e-10: 67.3: 10.41		STK39_HUMAN (68-530): 2.53e-105: 328: 14.96