HitPredict

Interactor 1: T22D1 (Q15714)
TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)
Gene: TSC22D1

Interactor 2: T22D4 (Q9Y3Q8)
TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2)
Gene: TSC22D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TSC22~TSC22
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1073 Hs			1 395
+	Mm
		914590 T22D1_MOUSE (1-1073): 2.42e-71: 260: 82.78		T22D4_MOUSE (1-395): 8.9e-60: 200: 84.56
+	Hs
		1077293 T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00		T22D1_HUMAN (28-394): 4.95e-38: 148: 26.81
+	Hs
		1077329 T22D1_HUMAN (1-1073): 7.61e-82: 291: 100.00		T22D3_HUMAN (276-395): 2.33e-27: 107: 49.59
+	Ce
		1094919 TSCT1_CAEEL (852-1044): 1.84e-30: 123: 30.50		Q9U290_CAEEL (22-386): 6.51e-31: 126: 13.95
+	Ce
		1094915 TSCT1_CAEEL (852-1044): 1.84e-30: 123: 30.50		TSCT1_CAEEL (134-375): 3.79e-32: 124: 26.09
+	Hs
		554259 MUC1_HUMAN (241-1069): 1.4e-45: 181: 9.20		MUC1_HUMAN (26-392): 5.69e-09: 60.3: 12.50
+	Hs
		256841 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		T22D2_HUMAN (23-388): 4.37e-28: 118: 27.69
+	Hs
		256822 T22D3_HUMAN (959-1060): 8.88e-24: 99.9: 67.96		T22D2_HUMAN (23-388): 4.37e-28: 118: 27.69
+	Hs
		1077313 KMT2C_HUMAN (475-1071): 1.01e-09: 65.4: 8.46		T22D1_HUMAN (28-394): 4.95e-38: 148: 26.81
+	Hs
		1304685 T22D4_HUMAN (817-1056): 3.61e-23: 105: 34.15		T22D3_HUMAN (276-395): 2.33e-27: 107: 49.59
+	Hs
		1304675 T22D3_HUMAN (959-1060): 8.88e-24: 99.9: 67.96		T22D3_HUMAN (276-395): 2.33e-27: 107: 49.59
+	Mm
		1351630 PCLO_MOUSE (593-1073): 3.11e-14: 80.1: 8.88		PCLO_MOUSE (5-281): 1.29e-12: 71.9: 13.06
+	Dm
		113976 M9PB30_DROME (2-390): 5.96e-11: 69.3: 8.42		M9PB30_DROME (17-393): 2.17e-11: 68: 13.52
+	Hs
		256819 T22D2_HUMAN (230-642): 1.86e-10: 67.3: 10.41		TITIN_HUMAN (5-287): 1.18e-10: 65.7: 11.75