HitPredict

Interactor 1: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29395067, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 523
+	Hs
		1069687 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613470 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1055876 ELAV3_HUMAN (1-326): 4.41e-84: 259: 62.82		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		516495 PABP4_HUMAN (6-240): 1.05e-46: 168: 21.34		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1031344 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1077415 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		RAVR1_HUMAN (84-234): 5.69e-14: 76.4: 23.35
+	Hs
		1020265 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1077376 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Dm
		114303 M9PBZ2_DROME (15-326): 4.1e-81: 261: 52.99		Q9VYI0_DROME (10-157): 7.3e-15: 78: 24.52
+	Dm
		114290 M9PBZ2_DROME (15-326): 4.1e-81: 261: 52.99		M9PBZ2_DROME (84-157): 1.35e-13: 75.3: 31.25
+	Hs
		1020259 ELAV3_HUMAN (1-326): 4.41e-84: 259: 62.82		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Dm
		114292 M9PBZ2_DROME (15-326): 4.1e-81: 261: 52.99		ELAV_DROME (84-157): 1.77e-12: 71.4: 27.50
+	Dm
		1375736 Q9VYI0_DROME (3-325): 4.64e-77: 241: 51.16		Q9VYI0_DROME (10-157): 7.3e-15: 78: 24.52
+	Dm
		562818 Q9VYI0_DROME (3-325): 4.64e-77: 241: 51.16		ELAV_DROME (84-157): 1.77e-12: 71.4: 27.50
+	Dm
		562814 ELAV_DROME (2-325): 2.03e-72: 233: 45.61		ELAV_DROME (84-157): 1.77e-12: 71.4: 27.50
+	Hs
		474021 PABP4_HUMAN (6-240): 1.05e-46: 168: 21.34		PAB4L_HUMAN (147-425): 7.96e-26: 110: 13.89
+	Hs
		1020249 PABP4_HUMAN (6-240): 1.05e-46: 168: 21.34		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65