HitPredict

Interactor 1: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Interactor 2: PTBP2 (Q9UKA9)
Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein)
Gene: PTBP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	29395067, 22365833
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~RRM_5
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 531
+	Hs
		643518 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		PTBP1_HUMAN (1-531): 3.71e-124: 376: 66.43
+	Hs
		321088 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		PTBP3_HUMAN (1-531): 3.32e-114: 350: 65.10
+	Hs
		541020 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		HNRPL_HUMAN (47-529): 6.83e-62: 215: 23.00
+	Hs
		321063 ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23		PTBP3_HUMAN (1-531): 3.32e-114: 350: 65.10
+	Hs
		1031344 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		PABP4_HUMAN (47-280): 1.83e-30: 127: 12.03
+	Hs
		1020265 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		ELAV2_HUMAN (327-530): 9.38e-25: 107: 15.81
+	Hs
		1077389 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		RBM20_HUMAN (57-182): 5.29e-22: 102: 34.65
+	Hs
		1020259 ELAV3_HUMAN (1-326): 4.41e-84: 259: 62.82		ELAV2_HUMAN (327-530): 9.38e-25: 107: 15.81
+	Dm
		114292 M9PBZ2_DROME (15-326): 4.1e-81: 261: 52.99		ELAV_DROME (316-527): 2.15e-20: 96.1: 16.46
+	Hs
		311347 ELAV1_HUMAN (1-326): 8.27e-90: 273: 100.00		CELF2_HUMAN (109-262): 1.23e-11: 68.9: 16.46
+	Dm
		562818 Q9VYI0_DROME (3-325): 4.64e-77: 241: 51.16		ELAV_DROME (316-527): 2.15e-20: 96.1: 16.46
+	Dm
		562814 ELAV_DROME (2-325): 2.03e-72: 233: 45.61		ELAV_DROME (316-527): 2.15e-20: 96.1: 16.46
+	Zm
		8151 A0A1D6ELH4_MAIZE (6-238): 1.42e-44: 162: 23.11		A0A1D6Q1I5_MAIZE (39-332): 2.16e-40: 154: 26.81
+	Hs
		540986 ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23		HNRPL_HUMAN (47-529): 6.83e-62: 215: 23.00
+	Hs
		1020249 PABP4_HUMAN (6-240): 1.05e-46: 168: 21.34		ELAV2_HUMAN (327-530): 9.38e-25: 107: 15.81
+	Dm
		284196 O76876_DROME (20-199): 1.12e-47: 168: 46.11		Q8WR53_DROME (3-258): 1.21e-16: 85.1: 17.05
+	Dm
		284190 O76876_DROME (20-199): 1.12e-47: 168: 46.11		Q7KRS7_DROME (104-459): 3.03e-12: 71.2: 15.60
+	Hs
		1020292 ELAV2_HUMAN (212-322): 4.72e-22: 97: 25.23		CELF5_HUMAN (138-262): 3.44e-11: 67.4: 12.40