HitPredict

Interactor 1: NSDHL (Q15738)
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3)
Gene: NSDHL

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37931956
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 373 Hs			1 1104
+	Hs
		1311389 3BHS7_HUMAN (29-367): 6.84e-76: 240: 27.35		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		48366 NSDHL_HUMAN (1-373): 3.71e-121: 356: 100.00		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		48501 3BHS7_HUMAN (29-367): 6.84e-76: 240: 27.35		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32