Interactor 1: NSDHL (Q15738)
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3)
Gene: NSDHL

Interactor 2: 3BHS7 (Q9H2F3)
3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3-beta-HSD VII) (3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase) (C(27) 3-beta-HSD) (EC 1.1.1.-) (Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase) (EC 1.1.1.181)
Gene: HSD3B7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 3Beta_HSD~3Beta_HSD
Common GO terms GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005811 - lipid droplet
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 373
Hs

1 369
+ Hs
+ Sp
+ At
+ At
+ At
+ Ec
+ Hs
+ Cj
+ Dm
+ At
+ Cj

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024