HitPredict

Interactor 1: TAB1 (Q15750)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)
Gene: TAB1

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	11865055
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BIR~PP2C
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 298
+	Hs
		1035783 TAB1_HUMAN (1-504): 0: 525: 100.00		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Hs
		1077901 TAB1_HUMAN (1-504): 0: 525: 100.00		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		1023638 TAB1_HUMAN (1-504): 0: 525: 100.00		BIRC1_HUMAN (81-158): 3.76e-14: 74.6: 32.91
+	Hs
		957710 TAB1_HUMAN (1-504): 0: 525: 100.00		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19
+	At
		286693 P2C63_ARATH (1-389): 3.49e-81: 259: 19.07		KN7D_ARATH (156-298): 6.16e-23: 100: 18.63
+	At
		1259222 P2C74_ARATH (7-427): 1.63e-79: 257: 16.36		KN7D_ARATH (156-298): 6.16e-23: 100: 18.63