Interactor 1: HERC1 (Q15751)
Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619)
Gene: HERC1

Interactor 2: RPGF5 (Q92565)
Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF) (Related to Epac) (Repac)
Gene: RAPGEF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 4861
Hs

1 580
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024