HitPredict

Interactor 1: NCOA1 (Q15788)
Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1)
Gene: NCOA1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 11003650, 15615775, 11113179, 11971985, 9192892, 16860316, 12163591, 14722092
Identification Methods far western blotting, affinity chromatography technology, pull down, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Creb_binding~Nuc_rec_co-act
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0004402 - histone acetyltransferase activity
GO:0005634 - nucleus
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1441
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024