HitPredict

Interactor 1: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Interactor 2: ARI1B (Q8NFD5)
AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R)
Gene: ARID1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16751102
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 467 Hs			1 2319
+	Hs
		171421 SMAD9_HUMAN (1-467): 0: 564: 54.56		ARI1B_HUMAN (21-2319): 0: 845: 100.00
+	Hs
		782329 SMAD3_HUMAN (1-467): 0: 617: 83.94		KDM5C_HUMAN (1099-1341): 1.93e-40: 167: 19.76
+	Hs
		1057763 SMAD2_HUMAN (1-467): 0: 675: 100.00		NCOA6_HUMAN (218-1914): 1.29e-21: 105: 11.36
+	Mm
		503177 SMAD2_MOUSE (1-467): 0: 675: 99.57		CO1A1_MOUSE (846-1724): 1.98e-17: 91.9: 11.46
+	Hs
		146229 SMAD2_HUMAN (1-467): 0: 675: 100.00		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		358519 SMAD2_HUMAN (1-467): 0: 675: 100.00		CO1A1_HUMAN (6-504): 9.46e-11: 69.9: 14.20
+	Hs
		1078590 SMAD2_HUMAN (1-467): 0: 675: 100.00		KMT2C_HUMAN (598-1634): 5.9e-09: 64: 11.53
+	Hs
		950184 SMAD3_HUMAN (1-467): 0: 617: 83.94		NCOA6_HUMAN (218-1914): 1.29e-21: 105: 11.36
+	Mm
		503178 SMAD3_MOUSE (1-467): 0: 617: 83.94		CO1A1_MOUSE (846-1724): 1.98e-17: 91.9: 11.46
+	Hs
		146196 SMAD3_HUMAN (1-467): 0: 617: 83.94		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		358494 SMAD3_HUMAN (1-467): 0: 617: 83.94		CO1A1_HUMAN (6-504): 9.46e-11: 69.9: 14.20
+	Hs
		1057764 SMAD1_HUMAN (1-467): 0: 565: 55.53		NCOA6_HUMAN (218-1914): 1.29e-21: 105: 11.36
+	Mm
		57764 SMAD1_MOUSE (1-467): 0: 566: 55.42		ARI1A_MOUSE (33-1422): 3.42e-18: 94.6: 8.98
+	Mm
		503173 SMAD4_MOUSE (11-456): 1.37e-150: 441: 31.46		CO1A1_MOUSE (846-1724): 1.98e-17: 91.9: 11.46
+	Hs
		358510 SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58		CO1A1_HUMAN (6-504): 9.46e-11: 69.9: 14.20
+	Mm
		192481 SMAD7_MOUSE (13-443): 5.17e-112: 338: 25.00		CO1A1_MOUSE (846-1724): 1.98e-17: 91.9: 11.46