HitPredict

Interactor 1: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Interactor 2: RSF1 (Q96T23)
Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)
Gene: RSF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20195357
Identification Methods	display technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 467 Hs			1 1441
+	Hs
		1021407 SMAD2_HUMAN (1-467): 0: 675: 100.00		ANK3_HUMAN (112-1387): 8.01e-51: 201: 9.42
+	Hs
		950161 SMAD3_HUMAN (1-467): 0: 617: 83.94		ANK3_HUMAN (112-1387): 8.01e-51: 201: 9.42
+	Hs
		1078590 SMAD2_HUMAN (1-467): 0: 675: 100.00		KMT2C_HUMAN (830-1420): 8.08e-19: 95.9: 11.64
+	Hs
		782329 SMAD3_HUMAN (1-467): 0: 617: 83.94		KDM5C_HUMAN (754-972): 3.88e-26: 119: 20.89
+	Hs
		171398 SMAD9_HUMAN (1-467): 0: 564: 54.56		PLEC_HUMAN (101-1361): 2.59e-41: 169: 11.90
+	Hs
		152653 SMAD1_HUMAN (1-467): 0: 565: 55.53		KMT2D_HUMAN (881-1008): 1.91e-10: 68.1: 21.88
+	Hs
		152555 SMAD9_HUMAN (1-467): 0: 564: 54.56		KMT2D_HUMAN (881-1008): 1.91e-10: 68.1: 21.88
+	Hs
		1035558 SMAD4_HUMAN (11-456): 4.53e-151: 443: 31.58		UHRF2_HUMAN (882-986): 2.33e-24: 112: 27.03