Interactor 1: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Interactor 2: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.868

The method score is based on:

Property Details
Experiments 9111321, 15231748, 11779505
Identification Methods two hybrid, x-ray crystallography, cosedimentation through density gradient, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MH1~MH1, MH2~MH2
Common GO terms GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 51 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 465
Hs

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Last updated: 15 Jul 2024