HitPredict

Interactor 1: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 22558309, 21712076
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, PH_13~RhoGEF, RhoGEF~RhoGEF, RhoGEF~SH3_1, RhoGEF~SH3_9, SH3_1~SH3_1, SH3_1~SH3_2, SH3_2~SH3_2, SH3_2~SH3_9, SH3_9~SH3_9
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005509 - calcium ion binding
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 17 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1721
Hs

1 1721
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024