HitPredict

Interactor 1: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1721 Hs			1 1374
+	Hs
		1168427 ITSN2_HUMAN (1-1720): 0: 723: 54.73		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		665608 ITSN1_HUMAN (1-1721): 0: 897: 100.00		EPHB2_HUMAN (6-404): 5.81e-122: 408: 22.77
+	Hs
		508022 ITSN1_HUMAN (1-1721): 0: 897: 100.00		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		433781 ITSN1_HUMAN (1-1721): 0: 897: 100.00		LYN_HUMAN (109-410): 9.62e-106: 347: 24.75
+	Hs
		1300028 ITSN2_HUMAN (1-1720): 0: 723: 54.73		LMTK3_HUMAN (7-1342): 9.67e-159: 518: 29.10
+	Hs
		601605 ITSN2_HUMAN (1-1720): 0: 723: 54.73		FGFR2_HUMAN (17-456): 6.43e-126: 412: 19.75
+	Hs
		508233 ITSN2_HUMAN (1-1720): 0: 723: 54.73		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		279869 TRIO_HUMAN (154-1590): 1.54e-71: 269: 10.81		NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54
+	Hs
		224698 KALRN_HUMAN (61-1630): 2.49e-75: 281: 11.31		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		224699 KALRN_HUMAN (61-1630): 2.49e-75: 281: 11.31		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		279830 TRIO_HUMAN (154-1590): 1.54e-71: 269: 10.81		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		411673 FGD1_HUMAN (1066-1664): 3.93e-73: 267: 16.32		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		279832 TRIO_HUMAN (154-1590): 1.54e-71: 269: 10.81		LYN_HUMAN (109-410): 9.62e-106: 347: 24.75
+	Hs
		506595 BCR_HUMAN (732-1682): 1.5e-71: 266: 12.45		DDR2_HUMAN (108-395): 1.06e-36: 152: 33.86
+	Hs
		279829 TRIO_HUMAN (154-1590): 1.54e-71: 269: 10.81		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		435784 ARHGC_HUMAN (648-1635): 3.19e-67: 253: 15.32		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		384168 BCR_HUMAN (732-1682): 1.5e-71: 266: 12.45		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		385628 ARHGC_HUMAN (648-1635): 3.19e-67: 253: 15.32		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		789009 ARHGC_HUMAN (648-1635): 3.19e-67: 253: 15.32		TEC_HUMAN (119-412): 1.84e-31: 134: 30.07
+	Hs
		337325 BCR_HUMAN (732-1682): 1.5e-71: 266: 12.45		ABL1_HUMAN (588-1118): 4.91e-10: 66.4: 13.32