HitPredict

Interactor 1: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Interactor 2: WBP11 (Q9Y2W2)
WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1)
Gene: WBP11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.620

Property	Details
Experiments	35914814, 18654987
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1721 Hs			1 641
+	Hs
		203228 ITSN1_HUMAN (1-1721): 0: 897: 100.00		SYNJ1_HUMAN (279-640): 1.85e-13: 76: 10.43
+	Hs
		257713 ITSN2_HUMAN (1-1720): 0: 723: 54.73		ANR17_HUMAN (125-603): 3.77e-10: 65.6: 12.66
+	Ce
		136804 VAV_CAEEL (1160-1566): 7.98e-66: 245: 16.74		UNC89_CAEEL (45-513): 1.61e-20: 99.1: 12.74
+	Hs
		855816 VAV2_HUMAN (612-1210): 1.5e-14: 81.3: 11.88		TITIN_HUMAN (179-535): 1.3e-09: 64: 13.13
+	Hs
		203230 SH319_HUMAN (1079-1218): 3.12e-09: 63.9: 28.57		SYNJ1_HUMAN (279-640): 1.85e-13: 76: 10.43
+	Hs
		203208 NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75		SYNJ1_HUMAN (279-640): 1.85e-13: 76: 10.43
+	Rn
		1126747 Q5JC29_RAT (529-841): 5.46e-10: 66.6: 12.00		SYNJ1_RAT (269-638): 9.72e-11: 67.5: 11.69
+	Hs
		557740 NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75		MINK1_HUMAN (381-554): 4.7e-10: 64.9: 23.56