HitPredict

Interactor 1: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 145 Hs			1 1208
+	Hs
		1205159 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		DZIP3_HUMAN (1-1208): 0: 1250: 100.00
+	Hs
		849362 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		DZIP3_HUMAN (1-1208): 0: 1250: 100.00
+	Hs
		196372 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		PJA2_HUMAN (601-1207): 1.64e-59: 220: 14.47
+	Hs
		196282 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		PJA2_HUMAN (601-1207): 1.64e-59: 220: 14.47
+	Hs
		196294 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		PJA2_HUMAN (601-1207): 1.64e-59: 220: 14.47
+	Hs
		865028 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		TTC3_HUMAN (703-1207): 1.23e-42: 173: 19.15
+	Hs
		1170316 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		ARK2C_HUMAN (1008-1191): 3.26e-29: 122: 17.74
+	Hs
		849350 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		ARK2C_HUMAN (1008-1191): 3.26e-29: 122: 17.74
+	Hs
		1148281 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		849341 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Zm
		39810 B4FCQ9_MAIZE (10-145): 2.96e-60: 184: 24.09		A0A1D6N2L7_MAIZE (1078-1193): 5.69e-25: 106: 21.19
+	Hs
		919752 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		1356934 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		RN150_HUMAN (1102-1202): 2.69e-22: 103: 21.36
+	Hs
		849485 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RN150_HUMAN (1102-1202): 2.69e-22: 103: 21.36
+	Hs
		1204871 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		GOLI_HUMAN (1107-1194): 1.08e-21: 101: 23.33
+	Hs
		849359 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		GOLI_HUMAN (1107-1194): 1.08e-21: 101: 23.33
+	Hs
		849382 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RN128_HUMAN (1112-1206): 2.54e-21: 100: 26.73
+	Zm
		74334 B4FC97_MAIZE (10-144): 1.66e-58: 180: 24.27		B6U926_MAIZE (1112-1204): 4.67e-22: 101: 26.60
+	Zm
		79637 B6SZE0_MAIZE (10-144): 1.24e-58: 180: 22.79		B6U926_MAIZE (1112-1204): 4.67e-22: 101: 26.60
+	At
		715137 UBC9_ARATH (10-144): 1.32e-58: 180: 23.53		RNG1L_ARATH (1112-1203): 4.05e-21: 97.9: 25.81