HitPredict

Interactor 1: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Interactor 2: RFFL (Q8WZ73)
E3 ubiquitin-protein ligase rififylin (EC 2.3.2.27) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like) (RING-type E3 ubiquitin transferase rififylin)
Gene: RFFL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23695783
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 145 Hs			1 363
+	Hs
		849387 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RFFL_HUMAN (1-363): 9.46e-153: 436: 100.00
+	Hs
		957802 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		XIAP_HUMAN (205-363): 2.45e-38: 145: 21.56
+	Hs
		849308 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		XIAP_HUMAN (205-363): 2.45e-38: 145: 21.56
+	Hs
		282581 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RNF8_HUMAN (142-357): 1.21e-37: 142: 16.81
+	Hs
		849321 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		BIRC3_HUMAN (231-363): 4.4e-34: 134: 22.30
+	Hs
		849322 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		BIRC2_HUMAN (220-363): 1.71e-33: 132: 21.33
+	Hs
		1298970 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		BIRC8_HUMAN (205-363): 2.71e-34: 128: 20.36
+	Hs
		849413 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		BIRC8_HUMAN (205-363): 2.71e-34: 128: 20.36
+	Hs
		230183 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		MGRN1_HUMAN (188-360): 1.65e-27: 115: 17.98
+	Hs
		230126 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		MGRN1_HUMAN (188-360): 1.65e-27: 115: 17.98
+	Hs
		849400 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		BIRC7_HUMAN (207-363): 1.94e-28: 114: 19.75
+	Hs
		1282543 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		MUL1_HUMAN (238-363): 5.99e-24: 102: 27.41
+	At
		715118 UBC8_ARATH (10-144): 7.9e-59: 180: 23.53		LUL3_ARATH (223-360): 7.03e-25: 105: 22.07
+	Hs
		849394 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		MUL1_HUMAN (238-363): 5.99e-24: 102: 27.41
+	Hs
		1264347 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		MYLIP_HUMAN (292-362): 1.63e-20: 94.2: 26.76
+	Hs
		849386 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		MYLIP_HUMAN (292-362): 1.63e-20: 94.2: 26.76
+	Hs
		849396 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		MIB2_HUMAN (270-361): 2.48e-17: 85.7: 26.04
+	Hs
		282379 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		NEUL1_HUMAN (297-363): 2.41e-17: 85.3: 31.94
+	Hs
		1206094 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		MIB1_HUMAN (305-362): 9.81e-10: 62.2: 31.03
+	Hs
		849363 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		MIB1_HUMAN (305-362): 9.81e-10: 62.2: 31.03