HitPredict

Interactor 1: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Interactor 2: HOIL1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: RBCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	30561431
Identification Methods	affinity chromatography technology, virotrap
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0000209 - protein polyubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 145 Hs			1 510
+	Hs
		1317101 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		849432 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		919847 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		HOIL1_HUMAN (1-510): 0: 577: 100.00
+	Hs
		849498 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		ARI1_HUMAN (216-496): 1.87e-68: 231: 18.09
+	Hs
		1354303 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		RNF14_HUMAN (242-478): 1.26e-68: 229: 18.99
+	Hs
		849474 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RNF14_HUMAN (242-478): 1.26e-68: 229: 18.99
+	Hs
		312679 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Hs
		312520 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Ce
		715114 UBC2_CAEEL (10-144): 7.08e-59: 180: 23.53		Q9XUS3_CAEEL (150-489): 1.62e-66: 221: 16.81
+	Hs
		312553 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85
+	Hs
		919757 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		RN19B_HUMAN (277-477): 1.57e-57: 205: 22.97
+	Hs
		919876 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		RN19A_HUMAN (256-477): 5.57e-57: 205: 16.60
+	Hs
		1347205 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		RN216_HUMAN (235-497): 5.21e-52: 191: 19.13
+	Hs
		849460 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		RN216_HUMAN (235-497): 5.21e-52: 191: 19.13
+	Hs
		229121 UB2D4_HUMAN (10-144): 9.98e-60: 183: 24.27		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		226914 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		919878 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		RN216_HUMAN (235-497): 5.21e-52: 191: 19.13
+	Hs
		227093 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80
+	Hs
		842095 UB2D1_HUMAN (10-145): 2.2e-59: 182: 24.82		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98
+	Hs
		842104 UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06		R144A_HUMAN (279-476): 3.85e-28: 115: 20.98