Interactor 1: CYTM (Q15828)
Cystatin-M (Cystatin-6) (Cystatin-E)
Gene: CST6
Interactor 2: LGMN (Q99538)
Legumain (EC 3.4.22.34) (Asparaginyl endopeptidase) (AEP) (Protease, cysteine 1)
Gene: LGMN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 1.00 | 0.860 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 25630877 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, molecular sieving, protease assay, enzymatic study, thermal shift binding, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, protein cleavage, enzymatic reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cystatin~Peptidase_C13 |
| Common GO terms | GO:0070062 - extracellular exosome |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
