Interactor 1: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Interactor 2: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 28205554, 12805220, 14676191, 20562859
Identification Methods fluorescent resonance energy transfer, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000287 - magnesium ion binding
GO:0001558 - regulation of cell growth
GO:0001894 - tissue homeostasis
GO:0001944 - vasculature development
GO:0002039 - p53 binding
and 60 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 433
Hs

1 433
+ At
+ At
+ Gm
+ At
+ At
+ Rn
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm
+ Hs
+ Hs
+ At

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Last updated: 15 Jul 2024