Interactor 1: STK11 (Q15831)
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)
Gene: STK11

Interactor 2: STRAA (Q7RTN6)
STE20-related kinase adapter protein alpha (STRAD alpha) (STE20-related adapter protein) (Serologically defined breast cancer antigen NY-BR-96)
Gene: STRADA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 21860411, 25852190, 28514442, 15561763, 12805220, 31554794, 33961781, 35271311, 32707033, 34591612, 37080995, 20562859, 14676191, 19513107, 26479318, 15733851
Identification Methods affinity chromatography technology, pull down, enzymatic study, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 433
Hs

1 431
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+ Hs
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+ Dm
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+ Ce

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Last updated: 15 Jul 2024