HitPredict

Interactor 1: G5EFX2 (G5EFX2)
protein kinase C (EC 2.7.11.13)
Gene: pkn-1

Interactor 2: RAC1 (Q03206)
Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)
Gene: ced-10

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	21277858
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HR1~Ras, Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1012 Ce			1 191
+	Ce
		104463 G5EFX2_CAEEL (1-1012): 0: 1148: 100.00		G5EBV3_CAEEL (2-191): 2.76e-79: 236: 62.63
+	Ce
		107920 G5EFX2_CAEEL (1-1012): 0: 1148: 100.00		RHO1_CAEEL (5-191): 1.92e-73: 221: 56.68
+	Hs
		925308 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		951021 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOG_HUMAN (1-191): 1.68e-79: 236: 66.49
+	Hs
		545401 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RAC2_HUMAN (1-191): 3.14e-79: 235: 79.17
+	Hs
		894056 PKN2_HUMAN (49-1010): 0: 1061: 35.88		CDC42_HUMAN (1-191): 1.95e-78: 233: 65.97
+	Hs
		900514 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOA_HUMAN (5-191): 2.1e-77: 231: 56.15
+	Hs
		1082034 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOJ_HUMAN (2-189): 3.05e-75: 226: 56.38
+	Hs
		436326 PKN2_HUMAN (49-1010): 0: 1061: 35.88		RHOC_HUMAN (5-191): 2.44e-75: 226: 54.55
+	Hs
		925307 PKN1_HUMAN (83-1010): 0: 945: 35.43		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		900513 PKN1_HUMAN (83-1010): 0: 945: 35.43		RHOA_HUMAN (5-191): 2.1e-77: 231: 56.15
+	Hs
		900594 PKN3_HUMAN (64-1010): 0: 904: 33.85		RHOA_HUMAN (5-191): 2.1e-77: 231: 56.15
+	Hs
		564425 AKT2_HUMAN (568-1010): 8.21e-157: 473: 34.15		RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87
+	Hs
		681775 AKT1_HUMAN (568-1010): 1.89e-155: 470: 34.38		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Sp
		736857 PCK2_SCHPO (598-1010): 3.37e-147: 466: 41.63		CDC42_SCHPO (1-191): 1.32e-79: 236: 66.15
+	Hs
		616691 KS6B1_HUMAN (595-1011): 1.23e-143: 440: 32.46		CDC42_HUMAN (1-191): 1.95e-78: 233: 65.97
+	Dm
		52723 PKN_DROME (657-1010): 8.04e-118: 392: 59.89		RAC1_DROME (1-191): 1.92e-79: 236: 81.25
+	Dm
		52739 A1Z7T1_DROME (657-1010): 1.25e-114: 387: 59.89		RAC1_DROME (1-191): 1.92e-79: 236: 81.25
+	Dm
		52724 PKN_DROME (657-1010): 8.04e-118: 392: 59.89		RHO1_DROME (5-191): 4.83e-74: 222: 55.08
+	Hs
		850632 KS6A3_HUMAN (558-960): 4.26e-100: 333: 19.52		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81