HitPredict

Interactor 1: STXB2 (Q15833)
Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B)
Gene: STXBP2

Interactor 2: STX19 (Q8N4C7)
Syntaxin-19
Gene: STX19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Sec1~Syntaxin
Common GO terms	GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 294
+	Mm
		192851 STXB2_MOUSE (1-593): 0: 706: 94.77		STX1A_MOUSE (8-288): 1.56e-68: 216: 28.72
+	Hs
		699262 STXB2_HUMAN (1-593): 0: 709: 100.00		STX2_HUMAN (24-288): 5.11e-65: 207: 26.32
+	Rn
		699178 STXB2_RAT (1-593): 0: 689: 93.94		STX1A_RAT (8-288): 2.27e-68: 215: 29.08
+	Hs
		269420 STXB2_HUMAN (1-593): 0: 709: 100.00		STX11_HUMAN (1-290): 1.64e-58: 190: 36.43
+	Rn
		838510 STXB2_RAT (1-593): 0: 689: 93.94		STX2_RAT (29-283): 8.99e-62: 199: 27.34
+	Hs
		1030144 STXB2_HUMAN (1-593): 0: 709: 100.00		STX3_HUMAN (1-281): 1.76e-52: 175: 29.08
+	Mm
		936823 STXB2_MOUSE (1-593): 0: 706: 94.77		STX4_MOUSE (8-289): 8.44e-54: 178: 25.00
+	Mm
		1145332 STXB2_MOUSE (1-593): 0: 706: 94.77		STX3_MOUSE (1-281): 3.24e-51: 171: 28.72
+	Rn
		996532 STXB2_RAT (1-593): 0: 689: 93.94		STX3_RAT (1-281): 1.79e-51: 172: 28.72
+	Bt
		699167 STXB1_BOVIN (1-591): 0: 632: 63.47		STX1A_BOVIN (8-288): 8.67e-69: 216: 28.72
+	Rn
		699173 STXB1_RAT (1-591): 0: 632: 63.47		STX1A_RAT (8-288): 2.27e-68: 215: 29.08
+	Hs
		901790 STXB1_HUMAN (1-591): 0: 632: 63.47		STX1A_HUMAN (8-288): 8.61e-68: 214: 28.72
+	Rn
		898824 STXB1_RAT (1-591): 0: 632: 63.47		STX1B_RAT (8-288): 3.71e-67: 212: 28.01
+	Hs
		898829 STXB1_HUMAN (1-591): 0: 632: 63.47		STX1B_HUMAN (8-288): 3.71e-67: 212: 28.01
+	Hs
		699253 STXB1_HUMAN (1-591): 0: 632: 63.47		STX2_HUMAN (24-288): 5.11e-65: 207: 26.32
+	Rn
		838509 STXB1_RAT (1-591): 0: 632: 63.47		STX2_RAT (29-283): 8.99e-62: 199: 27.34
+	Hs
		269405 STXB1_HUMAN (1-591): 0: 632: 63.47		STX11_HUMAN (1-290): 1.64e-58: 190: 36.43
+	Hs
		901776 STXB1_HUMAN (1-591): 0: 632: 63.47		STX4_HUMAN (8-289): 1.34e-56: 186: 27.47
+	Hs
		901780 STXB1_HUMAN (1-591): 0: 632: 63.47		STX3_HUMAN (1-281): 1.76e-52: 175: 29.08
+	Hs
		901809 STXB1_HUMAN (1-591): 0: 632: 63.47		STX19_HUMAN (1-294): 7.62e-48: 163: 100.00