HitPredict

Interactor 1: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Interactor 2: WDFY1 (Q8IWB7)
WD repeat and FYVE domain-containing protein 1 (FYVE domain-containing protein localized to endosomes 1) (FENS-1) (Phosphoinositide-binding protein 1) (WD40- and FYVE domain-containing protein 1) (Zinc finger FYVE domain-containing protein 17)
Gene: WDFY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 100 Hs			1 410
+	Hs
		926227 VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01		WDFY1_HUMAN (1-410): 7.71e-89: 276: 100.00
+	Hs
		1218461 VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07		WDFY1_HUMAN (1-410): 7.71e-89: 276: 100.00
+	Hs
		1079408 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		WDFY2_HUMAN (1-396): 4.19e-80: 253: 61.62
+	Sc
		605865 SEC22_YEAST (1-97): 1.07e-21: 86.2: 18.56		COPA_YEAST (1-383): 5.69e-22: 100: 12.44
+	Hs
		159947 VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01		HGS_HUMAN (276-351): 5.58e-15: 79: 42.11
+	Hs
		306845 VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57		SNR40_HUMAN (1-92): 3.86e-17: 84: 15.15
+	Hs
		263213 SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56		WDR5_HUMAN (1-96): 7.71e-15: 77.1: 12.87